Medical doctors usually prescribe an oral corticosteroid, like prednisone, together with an antihistamine to deal with delicate itchy rashes. However steroids, which carry dangers, even within the brief time period, is probably not wanted.
Researchers randomly assigned 100 adults with itchy hives to have every day remedy with both an antihistamine (levocetirizine, model title Xyzal) and prednisone, or the antihistamine and a sugar capsule. The examine is in Annals of Emergency Drugs.
Two days later, 62 p.c of the sufferers within the prednisone group reported that the itching had gone away, however so did 76 p.c of these within the placebo group. The rash had disappeared fully in 70 p.c of the prednisone group and in 78 p.c of the placebo group.
There have been no variations in opposed results between the 2 teams, and no variations within the variety of relapses after the remedy interval. The authors acknowledge that the information relies on self-reports from sufferers who weren’t examined clinically.
Based on the lead creator, Dr. Dominique Lauque, a professor of drugs on the College of Toulouse III in France, one cause docs nonetheless use steroids to deal with rash is that sufferers demand them. However, he stated, it’s higher to keep away from them when the rash is delicate.
Extra severe allergic reactions might require steroids, he continued, however in delicate circumstances, “I prescribe one of many new antihistamines.”