hydrocodone | Uncomfortable side effects, dosage, makes use of, and extra

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  1. Acetaminophen-hydrocodone oral pill is offered as a generic drug and as a brand-name drug. Model identify: Norco.
  2. Acetaminophen-hydrocodone comes as an oral pill and an oral answer.
  3. Acetaminophen-hydrocodone oral pill is used to deal with average to extreme ache that different remedies haven’t been in a position to relieve.

Acetaminophen-hydrocodone oral pill might make you are feeling sleepy, dizzy, or lightheaded. Keep away from driving a automotive or utilizing equipment till you know the way your physique reacts to this medicine.

This drug can even trigger different unintended effects.

Extra widespread unintended effects

The extra widespread unintended effects that may happen with acetaminophen-hydrocodone embrace:

  • sleepiness or drowsiness
  • feeling dizzy or lightheaded
  • nausea
  • vomiting
  • constipation

Severe unintended effects

Name your physician straight away when you’ve got severe unintended effects. Name 911 in case your signs really feel life threatening or for those who assume you’re having a medical emergency. Severe unintended effects and their signs can embrace the next:

  • Pores and skin rash
  • Swelling of your face, throat, and mouth
  • Liver issues, together with liver failure. Signs might embrace:
    • yellowing of your pores and skin and the whites of your eyes
    • ache within the higher proper a part of your abdomen space
    • swelling of your abdomen space
    • itchiness
    • confusion
    • feeling drained
    • lack of urge for food
  • Bother respiration
  • Drug dependence

Disclaimer: Our purpose is to offer you probably the most related and present info. Nevertheless, as a result of medicine have an effect on every particular person otherwise, we can’t assure that this info contains all doable unintended effects. This info will not be an alternative choice to medical recommendation. At all times talk about doable unintended effects with a healthcare skilled who is aware of your medical historical past.

Different warnings

  • Extreme allergic response warning: This medicine might trigger a extreme, doubtlessly life threatening allergic response. The response can happen in a short time. Signs might embrace:
    • bother respiration
    • swelling of your face, throat, and mouth
    • rash
    • itching
    • vomiting

If this happens, cease taking this medicine and name your physician straight away or get emergency medical assist.

  • Adrenal gland issues warning: This medicine might trigger your adrenal glands to not work as nicely. Signs might embrace:
    • nausea
    • vomiting
    • lack of urge for food
    • tiredness
    • weak point
    • dizziness
    • lightheadedness

You probably have these signs, speak together with your physician. You could have to cease taking this medicine or have some exams finished.

Acetaminophen-hydrocodone is a prescription medicine. As an opioid, it’s a managed substance. It comes as an oral pill and an oral answer.

Acetaminophen-hydrocodone oral pill is offered because the brand-name drug Norco. It’s additionally obtainable in its generic kind. Generic medicine normally price lower than brand-name medicine. In some circumstances, they might not be obtainable in each power or kind because the brand-name model.

This medicine is a mix of two or extra medicine in a single kind. It’s vital to find out about all of the medicine within the mixture as a result of every drug might have an effect on you another way.

Acetaminophen-hydrocodone oral tablets are used to deal with average to extreme ache that different remedies haven’t been in a position to relieve.

This medicine is a mix of the opioid (narcotic) hydrocodone and the analgesic (ache reliever) acetaminophen. Medical doctors prescribe each medicine to assist cut back their sufferers’ ache.

These medicine work within the mind to dam ache alerts and reduce the power to really feel ache. Hydrocodone can alter how the physique responds to ache, serving to an individual really feel extra snug.

Acetaminophen can even cut back a fever.

Acetaminophen-hydrocodone oral pill can work together with different drugs, nutritional vitamins, or herbs it’s possible you’ll be taking. An interplay is when a substance modifications the way in which a drug works. This may be dangerous or forestall the drug from working nicely.

To assist keep away from interactions, your physician ought to handle your whole drugs rigorously. Make sure you inform your physician about all drugs, nutritional vitamins, or herbs you’re taking. To learn how this drug may work together with one thing else you’re taking, speak together with your physician or pharmacist.

Examples of medication that may trigger interactions with acetaminophen-hydrocodone are listed beneath.

Medicine that trigger drowsiness

Taking sure medicine with acetaminophen-hydrocodone will increase your threat of drowsiness, dizziness, tiredness, and diminished bodily and psychological operate. If it’s essential to use one in every of these medicine with acetaminophen-hydrocodone, the dosage of 1 or each medicine needs to be diminished.

Examples of those medicine embrace:

Medicine that enhance serotonin

Taking this medicine with medicine that enhance the quantity of a chemical known as serotonin in your physique may cause a significant issue. This drawback, known as serotonin syndrome, might be deadly. Inform your physician if you’re taking any of those drugs:

  • some antidepressants (selective serotonin reuptake inhibitors [SSRIs], selective serotonin and norepinephrine reuptake inhibitors [SNRIs], tricyclic antidepressants [TCAs], monoamine oxidase inhibitors [MAOIs], mirtazapine, trazodone)
  • sure medicine for migraine (triptans)
  • sure medicine for nausea, reminiscent of ondansetron
  • tramadol, which is used for ache
  • linezolid, which is an antibiotic

Medicine that inhibit exercise of sure enzymes within the liver

Taking this medicine with medicine that may inhibit exercise of sure liver enzymes can enhance the quantity of hydrocodone in your physique and trigger extra unintended effects. You’ll have elevated respiration issues or drowsiness. Examples of those medicine embrace:

  • erythromycin
  • ketoconazole
  • protease inhibitors used to deal with HIV, reminiscent of ritonavir

Medicine that enhance exercise of sure enzymes within the liver

Taking this medicine with medicine that may enhance exercise of sure liver enzymes can decrease the quantity of hydrocodone or acetaminophen in your physique. You could want the next dose of this medicine to regulate your ache. Examples of those medicine embrace:

  • rifampin
  • carbamazepine
  • phenytoin

Disclaimer: Our purpose is to offer you probably the most related and present info. Nevertheless, as a result of medicine work together otherwise in every particular person, we can’t assure that this info contains all doable interactions. This info will not be an alternative choice to medical recommendation. At all times converse together with your healthcare skilled about doable interactions with all pharmaceuticals, nutritional vitamins, herbs and dietary supplements, and over-the-counter medicine that you’re taking.

This drug comes with a number of warnings.

Allergy warning

This drug may cause a extreme allergic response. Signs might embrace:

  • bother respiration
  • swelling of your throat or tongue
  • hives
  • rash
  • itching

In the event you develop these signs, name 911 or go to the closest emergency room.

Don’t take this drug once more for those who’ve ever had an allergic response to it. Taking it once more might be deadly (trigger demise).

Alcohol interplay warning

You shouldn’t drink alcohol whereas taking acetaminophen-hydrocodone. Ingesting alcohol whereas taking this medicine might trigger:

  • slowed or stopped respiration
  • drowsiness
  • tiredness
  • psychological cloudiness
  • bodily and psychological slowing

Combining alcohol with this drug additionally will increase your threat for liver issues and liver injury.

Withdrawal warning

All of a sudden stopping acetaminophen-hydrocodone might trigger withdrawal signs. Signs of withdrawal from acetaminophen-hydrocodone might embrace:

  • nausea, vomiting, or diarrhea
  • restlessness
  • extreme sweating
  • runny nostril
  • stomach cramps or ache
  • muscle aches
  • quick coronary heart charge
  • hypertension

Your threat for withdrawal signs is larger for those who’ve been taking excessive doses of this drug for a number of weeks or longer. Discuss together with your physician earlier than stopping acetaminophen-hydrocodone.

Warnings for folks with sure well being situations

For folks with head harm: You probably have a head harm, hydrocodone might trigger elevated strain in your mind and trigger respiration issues.

For folks with abdomen issues: Use warning taking this drug when you’ve got intestinal obstruction, ulcerative colitis, or constipation. This medicine might worsen your signs.

For folks with extreme kidney illness: This drug might construct up in your physique, which may trigger bother respiration and different unintended effects.

For folks with lung illness: You probably have lung illness, you may need bother respiration for those who take this medicine.

For folks with extreme liver illness: You probably have extreme liver illness, your threat of liver failure is elevated. Additionally, this drug might construct up in your physique, which may trigger bother respiration and different unintended effects.

For folks with prostate enlargement: You probably have an enlarged prostate, taking acetaminophen-hydrocodone might trigger elevated issue in urination.

For folks with bronchial asthma: You probably have extreme or uncontrolled bronchial asthma, don’t use this medicine with out speaking to your physician. You’ll have to take the primary few doses in a monitored setting.

For folks with seizures: You probably have epilepsy or have ever had seizures, inform your physician earlier than taking acetaminophen-hydrocodone. This drug might enhance your threat of seizures.

For pregnant ladies: This drug is a class C being pregnant drug. Which means two issues:

  1. Analysis in animals has proven adversarial results to the fetus when the mom takes the drug.
  2. There haven’t been sufficient research finished in people to make certain how the drug may have an effect on the fetus.

Inform your physician for those who’re pregnant or plan to change into pregnant. Infants born to moms who often take opioids reminiscent of hydrocodone could also be born bodily depending on this drug. This may trigger signs of withdrawal, or neonatal opioid withdrawal syndrome. Signs can embrace:

  • extreme crying
  • sneezing
  • shaking
  • fast respiration
  • elevated bowel actions
  • yawning
  • vomiting
  • fever

There’s additionally an elevated likelihood that the infant might have bother respiration if this medicine is given to the mom shortly earlier than giving delivery.

For ladies who’re breastfeeding: Acetaminophen is handed in small quantities in breast milk. Hydrocodone additionally passes into breast milk and will lead to extreme tiredness and slowed inhaling a baby who’s breastfed.

Breastfeeding whereas taking this medicine might include dangers. You and your physician ought to determine whether or not you’ll take this medicine or breastfeed.

For seniors: Older adults might have decreased kidney, liver, and coronary heart operate. In the event you’re a senior, your physician might begin you at a low dose of this medicine.

All doable dosages and drug varieties might not be included right here. Your dosage, drug kind, and the way usually you are taking the drug will depend upon:

  • your age
  • the situation being handled
  • the severity of your situation
  • different medical situations you’ve gotten
  • the way you react to the primary dose

Types and strengths

Generic: Acetaminophen-hydrocodone

  • Type: oral pill
  • Strengths:
    • hydrocodone 5 mg/acetaminophen 300 mg
    • hydrocodone 7.5 mg/acetaminophen 300 mg
    • hydrocodone 10 mg/acetaminophen 300 mg
    • hydrocodone 2.5 mg/acetaminophen 325 mg
    • hydrocodone 5 mg/acetaminophen 325 mg
    • hydrocodone 7.5 mg/acetaminophen 325 mg
    • hydrocodone 10 mg/acetaminophen 325 mg

Model: Norco

  • Type: oral pill
  • Strengths:
    • 2.5 mg hydrocodone/325 mg acetaminophen
    • 5 mg hydrocodone/325 mg acetaminophen
    • 7.5 mg hydrocodone/325 mg acetaminophen
    • 10 mg hydrocodone/325 mg acetaminophen

Dosage for average to extreme ache

Grownup dosage (ages 18 years and older and weighing a minimum of 101 kilos [46 kg])

  • 5 mg or 2.5 mg hydrocodone / 300 mg or 325 mg acetaminophen: The everyday dosage is 1–2 tablets taken each 4–6 hours as wanted. The utmost dosage is 8 tablets per day.
  • 7.5 mg or 10 mg hydrocodone / 300 mg or 325 mg acetaminophen: The everyday dosage is 1 pill taken 4–6 hours as wanted. The utmost dosage is 6 tablets per day.

Youngster dosage (ages 0–17 years)

  • Dosage for folks youthful than 18 years hasn’t been established.

Disclaimer: Our purpose is to offer you probably the most related and present info. Nevertheless, as a result of medicine have an effect on every particular person otherwise, we can’t assure that this record contains all doable dosages. This info will not be an alternative choice to medical recommendation. At all times converse together with your physician or pharmacist about dosages which might be best for you.

Acetaminophen-hydrocodone is used for short- or long-term therapy. It comes with dangers for those who don’t take it precisely as prescribed by your physician.

In the event you cease taking the drug or don’t take it in any respect: Your ache will proceed and may worsen.

In the event you miss doses or don’t take the drug on schedule: Your medicine might not work as nicely or might cease working fully. For this drug to work nicely, a specific amount must be in your physique always.

What to do for those who miss a dose: In the event you’re taking the medicine often, take the missed dose as quickly as you bear in mind. Skip the missed dose if it’s nearly time in your subsequent scheduled dose.

Don’t use further medicine to make up the missed dose. This might lead to harmful unintended effects.

Learn how to inform if the drug is working: Your ache ought to lower.

It’s doable to overdose on this medicine if an individual takes an excessive amount of. Your physician might advocate that you’ve naloxone (Narcan) obtainable. This medicine helps reverse an opioid overdose if it’s obtainable and might be given in time. Signs of an acetaminophen-hydrocodone overdose might embrace:

  • nausea and vomiting
  • sweating
  • fatigue
  • slowed or stopped respiration
  • slowed coronary heart charge

If an individual thinks that they’ve taken an excessive amount of of this drug, they need to name their physician or search steering from the American Affiliation of Poison Management Facilities at 1-800-222-1222 or by way of their on-line device.

If signs are extreme, an individual ought to name 911 or go to the closest emergency room straight away.

Some acetaminophen-hydrocodone drugs might include different medicine, reminiscent of aspirin, ibuprofen, and antihistamines.

You will need to by no means take any of those substances individually if a health care provider has already prescribed a mixed medicine, as this may trigger an overdose.

Preserve these concerns in thoughts in case your physician prescribes acetaminophen-hydrocodone for you.

Basic

  • Take with meals to decrease your threat of upset abdomen.
  • You may lower or crush the oral pill.

Storage

  • Retailer this drug at temperatures starting from 68°F to 77°F (20°C to 25°C).
  • Preserve this in a container with a child-resistant closure.
  • Preserve this drug away from gentle.

Refills

A prescription for this medicine will not be refillable. You or your pharmacy should contact your physician for a brand new prescription for those who want this medicine refilled.

Journey

When touring together with your medicine:

  • At all times carry your medicine with you. When flying, by no means put it right into a checked bag. Preserve it in your carry-on bag.
  • Don’t fear about airport X-ray machines. They will’t damage your medicine.
  • You could want to indicate airport employees the pharmacy label in your medicine. At all times carry the unique prescription-labeled container with you.
  • Don’t put this medicine in your automotive’s glove compartment or go away it within the automotive. Make sure you keep away from doing this when the climate could be very scorching or very chilly.

Medical monitoring

Your physician might do sure exams to test whether or not you’ve gotten extreme liver or kidney illness. These exams will test your:

  • Kidney operate. Your physician might do kidney exams when you’ve got kidney issues to make it possible for this medicine is protected for you and gained’t trigger respiration issues.
  • Liver operate. Your physician might do liver exams when you’ve got liver issues to make it possible for this medicine is protected for you and gained’t trigger respiration issues.

Prior authorization

Most insurance coverage corporations don’t require a previous authorization for this drug.

There are different medicine obtainable to deal with your situation. Some could also be extra appropriate for you than others. Discuss together with your physician about different drug choices which will give you the results you want.

Disclaimer: Medical Information Right this moment has made each effort to make sure that each one info is factually right, complete, and updated. Nevertheless, this text shouldn’t be used as an alternative choice to the information and experience of a licensed healthcare skilled. You must at all times seek the advice of your physician or one other healthcare skilled earlier than taking any medicine. The drug info contained herein is topic to vary and isn’t supposed to cowl all doable makes use of, instructions, precautions, warnings, drug interactions, allergic reactions, or adversarial results. The absence of warnings or different info for a given drug doesn’t point out that the drug or drug mixture is protected, efficient, or acceptable for all sufferers or all particular makes use of.

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