I’ve taken Zyrtec day by day for over 4 years to handle animal and seasonal allergic reactions. I not too long ago went on trip and didn’t take Zyrtec throughout that point. (I used to be away from the allergy sources, in any case.)
After a couple of days off the medication, I developed a sudden and excruciating itching. Oddly, it felt prefer it got here from inside my physique slightly than on the floor. The itch began in my interior thighs and unfold to my sides and again.
Fortunately, I went on-line and searched the reactions I used to be having. My signs matched these of others who stopped Zyrtec abruptly.
As soon as I noticed this was a withdrawal response, I took a Zyrtec tablet. Throughout the hour the itching stopped. Now I’m afraid to ever cease taking Zyrtec. The itch was very intense, and I do not need to undergo that once more!
A. Readers of this column alerted us to this withdrawal phenomenon almost a decade in the past. At the moment, cetirizine (Zyrtec) was out there solely by prescription. The prescribing info didn’t warn a couple of withdrawal itch response.
The Meals and Drug Administration has now acknowledged that many individuals expertise insufferable itching (pruritus) once they cease cetirizine abruptly (Therapeutic Advances in Drug Security, July 5, 2019). In line with the report: “Some sufferers described the itch as so intense that it impacted their capability to work, sleep, or carry out their regular day by day actions …”
The company now requires a warning about this withdrawal response within the prescribing info for each cetirizine and its chemical cousin levocetirizine (Xyzal). So far as we will inform, nonetheless, this alert isn’t included within the over-the-counter labels.
I take sildenafil (Viagra) for erectile dysfunction. It really works fairly properly. However not lengthy after taking it I expertise fairly disagreeable heartburn. For sure, this interferes with the romantic temper. Do you’ve got any suggestions?
All the erectile dysfunction medicine (sildenafil, tadalafil and vardenafil, aka Viagra, Cialis and Levitra) may cause heartburn as a aspect impact. They work by stress-free clean muscle that strains the blood vessels going into the penis. Nonetheless, clean muscle elsewhere within the physique, corresponding to that within the decrease esophageal sphincter within the digestive tract, additionally relaxes in response to those medicine. That promotes acid reflux disease.
Ask your physician whether or not taking an antacid like Tums or Rolaids alongside along with your sildenafil would possibly relieve heartburn. An alternative choice is likely to be an acid-suppressing H2 antagonist like cimetidine (Tagamet), famotidine (Pepcid) or ranitidine (Zantac).
A variety of years in the past my prescription for Zoloft was modified to generic sertraline. It concurrently grew to become ineffective.
Because of this, my physician started including different medicine to the generic sertraline to attempt to obtain a response in opposition to melancholy. After a number of makes an attempt at completely different add-ons, I used to be prescribed generic Budeprion XL 300. Three days later I suffered a grand mal seizure.
I give up all melancholy drugs then and have suffered by main melancholy since that point. That appears marginally higher than coping with the possibly life-threatening uncomfortable side effects of those generic medicine. I am not keen to be a guinea pig!
We doc generic drug failures on the whole, and the Budeprion XL 300 debacle specifically, in our e book “High Screwups Medical doctors Make and Keep away from Them.” As a result of there are flaws within the FDA’s system of approving and monitoring generic drugs, you might need to learn our high 10 ideas for taking generic medicine properly in “High Screwups.” It’s out there for buy at www.PeoplesPharmacy.com.
Of their column, Joe and Teresa Graedon reply letters from readers. Write to them in care of King Options, 628 Virginia Drive, Orlando, FL 32803, or e mail them through their web site: www.PeoplesPharmacy.com. Their latest e book is “High Screwups Medical doctors Make and Keep away from Them.”