Facet Results, Dosage, Makes use of, and Extra

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Highlights for rabeprazole

  1. Rabeprazole oral pill is accessible as each a generic and brand-name drug. Model identify: Aciphex.
  2. Rabeprazole additionally comes as an oral capsule. Each the rabeprazole pill and capsule are delayed-release. This implies the remedy is slowly launched into your physique over time.
  3. Rabeprazole is used to deal with a number of gastrointestinal (GI) situations. These situations are attributable to excessive ranges of acid produced by the abdomen.

Rabeprazole oral pill doesn’t trigger drowsiness. Nonetheless, it may well trigger different unintended effects.

Extra widespread unintended effects

The extra widespread unintended effects of rabeprazole can embody:

  • headache
  • ache within the stomach (abdomen space)
  • sore throat
  • fuel
  • an infection
  • constipation
  • diarrhea

If these results are gentle, they could go away inside just a few days or a few weeks. In the event that they’re extra extreme or don’t go away, discuss to your physician or pharmacist.

Critical unintended effects

Name your physician immediately when you’ve got severe unintended effects. Name 911 in case your signs really feel life-threatening or if you happen to assume you’re having a medical emergency. Critical unintended effects and their signs can embody the next:

  • Low ranges of magnesium (a mineral). Signs can embody:
    • seizures
    • dizziness
    • irregular or quick heartbeat
    • jitteriness
    • tremors (jerking actions or shaking)
    • muscle weak point
    • spasms of the arms and ft
    • cramps or muscle aches
    • spasm of the voice field, with signs resembling hassle respiration, coughing, wheezing, hoarse voice, or throat tightness
  • Extreme diarrhea (attributable to an infection with C. difficile). Signs can embody:
    • watery stool
    • abdomen ache
    • fever
  • Cutaneous lupus erythematosus (CLE). Signs can embody:
    • rash on the pores and skin and nostril
    • raised, purple, scaly, purple or purple rash in your physique
  • Systemic lupus erythematosus (SLE). Signs can embody:
    • fever
    • tiredness
    • weight reduction
    • blood clots
    • heartburn
  • Tubulointerstitial nephritis (TIN). Signs can embody:
    • a change within the quantity of urine you move
    • blood in your urine
    • important weight acquire

Disclaimer: Our purpose is to offer you essentially the most related and present info. Nonetheless, as a result of medicine have an effect on every particular person in a different way, we can not assure that this info contains all attainable unintended effects. This info is just not an alternative to medical recommendation. All the time focus on attainable unintended effects with a healthcare supplier who is aware of your medical historical past.

  • Extreme diarrhea warning: Rabeprazole raises your danger of extreme diarrhea. This diarrhea is attributable to an infection of the intestines by micro organism (Clostridium difficile). Speak to your physician when you’ve got watery stool, abdomen ache, or a fever that doesn’t go away.
  • Bone fractures warning: In the event you take a number of day by day doses of rabeprazole for an extended time period (1 12 months or longer), your danger of fractures of the hip, wrist, or backbone is elevated. This drug must be used on the lowest dose attainable. It also needs to be used for the shortest time wanted.
  • Low magnesium ranges warning: Rabeprazole could cause low ranges in your physique of a mineral known as magnesium. This normally occurs after 1 12 months of remedy. Nonetheless, it may well happen after you’re taking rabeprazole for 3 months or longer. Low magnesium ranges might not trigger any signs, however severe unintended effects can happen. These can embody muscle spasms, irregular coronary heart rhythms, or seizures.
  • Cutaneous lupus erythematosus and systemic lupus erythematosus warning: Rabeprazole could cause cutaneous lupus erythematosus (CLE) and systemic lupus erythematosus (SLE). CLE and SLE are autoimmune illnesses. Signs of CLE can vary from a rash on the pores and skin and nostril, to a raised, scaly, purple or purple rash on sure elements of the physique. Signs of SLE can embody fever, tiredness, weight reduction, blood clots, heartburn, and abdomen ache. When you’ve got any of those signs, name your physician.
  • Tubulointerstitial nephritis warning: Rabeprazole could cause acute tubulointerstitial nephritis (TIN), which is a situation that impacts your kidney operate. Signs of TIN might embody decreased urination, swelling, blood within the urine, nausea, rash, and exhaustion. Name your physician immediately if you happen to expertise any of those signs.

Rabeprazole oral pill is a prescription drug that’s obtainable because the brand-name drug Aciphex. It’s additionally obtainable as a generic drug. Generic medicine normally value lower than the brand-name model. In some instances, they is probably not obtainable in all strengths or kinds because the brand-name drug.

Rabeprazole additionally comes as an oral capsule. Each the rabeprazole pill and capsule are delayed-release kinds. This implies the remedy is slowly launched into your physique over time.

Why it’s used

Rabeprazole is used to deal with a number of gastrointestinal (GI) situations. These embody:

  • heartburn and different signs associated to gastroesophageal reflux illness (GERD). GERD happens when acid in your abdomen backs up into your esophagus (the tube that connects the mouth to the abdomen). This will trigger a burning feeling within the chest or throat, a bitter style within the mouth, or burping.
  • duodenal ulcers (sores within the first a part of the small gut), together with ulcers attributable to the bacterium H. pylori.
  • situations that trigger the abdomen to make an excessive amount of acid. These embody a uncommon situation known as Zollinger-Ellison syndrome.

Rabeprazole could also be used as a part of a mix remedy. This implies you could have to take it with different drugs. When rabeprazole is used to deal with an an infection attributable to the bacterium H. pylori, it’s utilized in mixture with two antibiotics. These are amoxicillin and clarithromycin.

The way it works

Rabeprazole belongs to a category of medication known as proton pump inhibitors. A category of medication is a gaggle of medicines that work in the same approach. These medicine are sometimes used to deal with comparable situations.

Rabeprazole works by decreasing the quantity of acid produced in your abdomen.

Rabeprazole oral pill can work together with different drugs, nutritional vitamins, or herbs you could be taking. An interplay is when a substance modifications the way in which a drug works. This may be dangerous or forestall the drug from working properly.

To assist keep away from interactions, your physician ought to handle your entire drugs fastidiously. Be sure you inform your physician about all drugs, nutritional vitamins, or herbs you’re taking. To learn the way this drug would possibly work together with one thing else you’re taking, discuss to your physician or pharmacist.

Examples of medication that may trigger interactions with rabeprazole are listed beneath.

Medication that you shouldn’t use with rabeprazole

Don’t take these medicine with rabeprazole. Doing so could cause harmful results within the physique. Examples of those medicine embody:

  • HIV medicine resembling atazanavir, nelfinavir, or rilpivirine. Utilizing these medicine with rabeprazole could cause very low ranges of those medicine in your physique. Consequently, they received’t work as properly.

Interactions that improve your danger of unintended effects

Taking rabeprazole with sure drugs raises your danger of unintended effects from these medicine. Examples of those medicine embody:

  • HIV medicine resembling saquinavir. Utilizing these medicine with rabeprazole could cause very excessive ranges of those medicine in your physique. This may end up in elevated unintended effects.
  • Warfarin. Elevated unintended effects can embody the next INR (blood check consequence). This might trigger irregular bleeding. Your physician might monitor your INR extra intently.
  • Cyclosporine. Your physician might monitor your cyclosporine blood ranges.
  • Methotrexate. You’ll have elevated unintended effects resulting from excessive ranges of methotrexate in your physique. Your physician might monitor the extent of methotrexate in your blood.
  • Digoxin. You’ll have elevated unintended effects resulting from excessive ranges of digoxin in your physique. Your physician might monitor the extent of digoxin in your blood.

Interactions that may make your medicine much less efficient

When sure medicine are used with rabeprazole, they could not work as properly. It is because the quantity of those medicine in your physique could also be decreased. Examples of those medicine embody:

  • Antifungal medicine resembling ketoconazole and itraconazole. Your physician might advise you to have an acidic drink, resembling cola, to assist your abdomen take in these medicine. Or your physician might cease your remedy with rabeprazole when you take these medicine to verify they work properly.
  • Mycophenolate mofetil. Your physician will probably monitor your remedy with mycophenolate mofetil. They could additionally regulate your dosage.
  • Iron salts. Your physician will probably monitor your iron ranges to verify they keep in a secure vary.
  • Most cancers medicine resembling erlotinib, dasatinib, and nilotinib. Your physician will probably monitor your physique’s response to those medicine to verify they work properly.

Disclaimer: Our purpose is to offer you essentially the most related and present info. Nonetheless, as a result of medicine work together in a different way in every particular person, we can not assure that this info contains all attainable interactions. This info is just not an alternative to medical recommendation. All the time converse along with your healthcare supplier about attainable interactions with all prescribed drugs, nutritional vitamins, herbs and dietary supplements, and over-the-counter medicine that you’re taking.

Rabeprazole oral pill comes with a number of warnings.

Allergy warning

Rabeprazole could cause a extreme allergic response. Signs can embody:

  • rash
  • swelling of your face
  • throat tightness
  • hassle respiration

When you’ve got an allergic response, name your physician or native poison management heart immediately. In case your signs are extreme, name 911 or go to the closest emergency room.

Don’t take this drug once more if you happen to’ve ever had an allergic response to it. Taking it once more could possibly be deadly (trigger demise).

Warnings for folks with sure well being situations

For folks with liver issues: When you’ve got liver issues or a historical past of liver illness, you could not be capable of clear this drug out of your physique properly. This may increasingly improve the degrees of rabeprazole in your physique and trigger extra unintended effects. When you’ve got extreme liver illness, discuss along with your physician about whether or not this drug is secure for you.

Warnings for different teams

For pregnant ladies: Speak to your physician if you happen to’re pregnant or planning to turn out to be pregnant. Research of this drug in pregnant animals haven’t proven danger to the fetus. Nonetheless, there is no such thing as a info obtainable about whether or not rabeprazole would hurt a human being pregnant. This drug ought to solely be used if the potential profit justifies potential danger.

Name your physician immediately if you happen to turn out to be pregnant whereas taking this drug.

Girls who’re breastfeeding: Rabeprazole might move into breast milk and should trigger unintended effects in a baby who’s breastfed. Speak to your physician if you happen to breastfeed your little one. You could have to determine whether or not to cease breastfeeding or cease taking this remedy.

For youngsters:

  • Rabeprazole tablets can be utilized in kids 12 years and older to deal with GERD for as much as 8 weeks.
  • It hasn’t been confirmed that rabeprazole is secure and efficient to deal with different GI situations in folks youthful than 18 years.

This dosage info is for rabeprazole oral pill. All attainable dosages and drug kinds is probably not included right here. Your dosage, drug type, and the way typically you’re taking the drug will rely upon:

  • your age
  • the situation being handled
  • how extreme your situation is
  • different medical situations you’ve
  • the way you react to the primary dose

Types and strengths

Generic: Rabeprazole

  • Kind: Oral pill
  • Strengths: 20 mg

Model: Aciphex

  • Kind: Oral pill
  • Strengths: 20 mg

Dosage for gastroesophageal reflux illness (GERD)

Grownup dosage (ages 18 years and older)

  • Typical dosage: 20 mg as soon as day by day.
  • The size of remedy will depend on your situation. It is going to be totally different when you’ve got acid-related injury in your esophagus, or if you happen to’re solely being handled for heartburn signs attributable to GERD.

Youngster dosage (ages 12–17 years)

Typical dosage: 20 mg as soon as day by day for as much as 8 weeks.

Youngster dosage (ages 0–11 years)

It hasn’t been confirmed that rabeprazole pill is secure and efficient to deal with GERD in kids youthful than 12 years.

Dosage for duodenal ulcers

Grownup dosage (ages 18 years and older)

Typical dosage: 20 mg as soon as day by day after the morning meal for as much as 4 weeks.

Youngster dosage (ages 0–17 years)

It hasn’t been confirmed that rabeprazole is secure and efficient to deal with duodenal ulcers in folks youthful than 18 years.

Dosage for ulcers attributable to Helicobacter pylori

Grownup dosage (ages 18 years and older)

  • Typical dosage: 20 mg twice day by day with morning and night meals for 7 days. To deal with ulcers attributable to H. pylori, this drug is utilized in mixture with the medicine amoxicillin and clarithromycin.

Youngster dosage (ages 0–17 years)

It hasn’t been confirmed that rabeprazole is secure and efficient to deal with duodenal ulcers attributable to the micro organism H. pylori in folks youthful than 18 years.

Dosage for situations that trigger the abdomen to make an excessive amount of acid, resembling Zollinger-Ellison syndrome

Grownup dosage (ages 18 years and older)

  • Typical beginning dosage: 60 mg as soon as day by day.
  • Dosage will increase: Your physician will improve your dosage as wanted.
  • Most dosage: 100 mg as soon as day by day, or 60 mg twice day by day.

Youngster dosage (ages 0–17 years)

It hasn’t been confirmed that rabeprazole is secure and efficient to deal with abdomen acid issues in folks youthful than 18 years.

Disclaimer: Our purpose is to offer you essentially the most related and present info. Nonetheless, as a result of medicine have an effect on every particular person in a different way, we can not assure that this checklist contains all attainable dosages. This info is just not an alternative to medical recommendation. All the time converse along with your physician or pharmacist about dosages which are best for you.

Rabeprazole oral pill is often used for short-term remedy. In some instances, it might be used for long-term remedy. It comes with severe dangers if you happen to don’t take it as prescribed.

In the event you cease taking the drug all of the sudden or don’t take it in any respect: The quantity of acid in your abdomen received’t be lowered. Consequently, your medical situation received’t be managed.

In the event you miss doses or don’t take the drug on schedule: Your remedy might not work as properly or might cease working fully. For this drug to work properly, a certain quantity must be in your physique always.

In the event you take an excessive amount of: You could possibly have harmful ranges of the drug in your physique. Signs of an overdose of this drug can embody:

  • tachycardia (quick coronary heart price)
  • flushing (sudden redness and heat within the face)
  • confusion
  • headache
  • blurry imaginative and prescient
  • ache within the stomach (abdomen space)
  • nausea or vomiting
  • drowsiness

In the event you assume you’ve taken an excessive amount of of this drug, name your physician or native poison management heart. In case your signs are extreme, name 911 or go to the closest emergency room immediately.

What to do if you happen to miss a dose: Take your dose as quickly as you keep in mind. However if you happen to keep in mind just some hours earlier than your subsequent scheduled dose, take just one dose. By no means attempt to catch up by taking two doses without delay. This might lead to harmful unintended effects.

Find out how to inform if the drug is working: You need to have much less ache in your GI system.

Maintain these concerns in thoughts in case your physician prescribes rabeprazole oral tablets for you.

Normal

  • Don’t chew, crush, or break up the rabeprazole tablets.
  • Not each pharmacy shares this drug. When filling your prescription, be sure you name forward to verify your pharmacy carries it.

Storage

  • Retailer rabeprazole at room temperature between 59°F and 86°F (15°C and 30°C).
  • Don’t retailer this remedy in moist or damp areas, resembling loos.

Refills

A prescription for this remedy is refillable. You shouldn’t want a brand new prescription for this remedy to be refilled. Your physician will write the variety of refills licensed in your prescription.

Journey

When touring along with your remedy:

  • All the time carry your remedy with you. When flying, by no means put it right into a checked bag. Maintain it in your carry-on bag.
  • Don’t fear about airport X-ray machines. They will’t harm your remedy.
  • You could want to indicate airport workers the pharmacy label to your remedy. All the time carry the unique prescription-labeled container with you.
  • Don’t put this remedy in your automotive’s glove compartment or depart it within the automotive. Be sure you keep away from doing this when the climate may be very sizzling or very chilly.

Medical monitoring

Rabeprazole can lower the degrees of vitamin B-12 in your blood. In the event you’ve been taking rabeprazole for greater than 3 years, discuss along with your physician about whether or not you need to take vitamin B-12 dietary supplements.

Your weight loss plan

Rabeprazole can lower the degrees of vitamin B-12 in your blood. In the event you’ve been taking rabeprazole for greater than 3 years, discuss along with your physician about whether or not you need to take vitamin B-12 dietary supplements..

Hidden prices

You could want blood exams to verify your magnesium stage. The price of these exams will rely in your insurance coverage protection.

Insurance coverage

Many insurance coverage corporations require a previous authorization for this drug. This implies your physician might want to get approval out of your insurance coverage firm earlier than your insurance coverage firm pays for the prescription.

There are different medicine obtainable to deal with your situation. Some could also be higher suited to you than others. Speak to your physician about different drug choices that will give you the results you want.

Disclaimer: Healthline has made each effort to make sure that every one info is factually right, complete, and up-to-date. Nonetheless, this text shouldn’t be used as an alternative to the data and experience of a licensed healthcare skilled. You need to all the time seek the advice of your physician or different healthcare skilled earlier than taking any remedy. The drug info contained herein is topic to vary and isn’t meant to cowl all attainable makes use of, instructions, precautions, warnings, drug interactions, allergic reactions, or adversarial results. The absence of warnings or different info for a given drug doesn’t point out that the drug or drug mixture is secure, efficient, or acceptable for all sufferers or all particular makes use of.

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